L-Methylfolate — Nutrient Associations & Health Patterns
Also known as: Levomefolate calcium (Deplin, Enlyte)
Drug Class: Medical food / Active folate
The biologically active form of folate (vitamin B9) used as adjunctive treatment for depression and for patients with MTHFR gene variants who cannot convert folic acid efficiently. Only evidence-qualified catalog relationships are listed here. Other catalog entries remain unverified in this reference; absence from the list does not rule out other medication effects or interactions.
Medication and Nutrition Context
Only evidence-qualified catalog relationships are listed here. Other catalog entries remain unverified in this reference; absence from the list does not rule out other medication effects or interactions.
Common Side Effects of L-Methylfolate
- Generally well-tolerated
- Rare: nausea
- Rare: bloating
- Rare: irritability
Key Drug Interactions — L-Methylfolate
L-Methylfolate has 6 documented drug-drug interactions in WePattern's Pattern Health Intelligence database. Key interactions include:
- Anticonvulsants (phenytoin, carbamazepine)
- Methotrexate
- NSAIDs
- Levothyroxine
- Quinolone antibiotics
- Tetracycline antibiotics
Frequently Asked Questions
What nutrient associations are reported for L-Methylfolate?
Only evidence-qualified catalog relationships are listed here. Other catalog entries remain unverified in this reference; absence from the list does not rule out other medication effects or interactions.
Which nutrient relationships are mapped for L-Methylfolate?
Only evidence-qualified catalog relationships are listed here. Other catalog entries remain unverified in this reference; absence from the list does not rule out other medication effects or interactions.
What are the side effects of L-Methylfolate?
Common side effects associated with L-Methylfolate include: Generally well-tolerated; Rare: nausea; Rare: bloating; Rare: irritability.