Metoclopramide — Nutrient Depletion & Health Patterns

Also known as: Metoclopramide hydrochloride (Reglan)

Drug Class: GI motility agent

Dopamine antagonist that increases GI motility and is used for gastroparesis, nausea, and GERD. Has a black box warning for tardive dyskinesia risk with use beyond 12 weeks.

Nutrients That Metoclopramide May Deplete

Long-term use of Metoclopramide is associated with lower levels of the following nutrients based on peer-reviewed clinical research. WePattern surfaces these patterns from its clinical Knowledge Graph.

Vitamin B12
Iron
Folate

Common Side Effects of Metoclopramide

Restlessness
Drowsiness
Fatigue
Dizziness
Tardive dyskinesia
Depression
Headache

Key Drug Interactions — Metoclopramide

Metoclopramide has 9 documented drug-drug interactions in WePattern's Pattern Health Intelligence database. Key interactions include:

MAO inhibitors
Levodopa
Antipsychotics
SSRIs
CNS depressants
Opioids

Frequently Asked Questions

Does Metoclopramide deplete nutrients?

Yes. Metoclopramide has been associated with depletion of Vitamin B12, Iron, Folate based on clinical research. WePattern maps these relationships from peer-reviewed sources.

What nutrients does Metoclopramide deplete?

Metoclopramide is associated with lower levels of: Vitamin B12, Iron, Folate. These depletions can develop over weeks to months of regular use.

What are the side effects of Metoclopramide?

Common side effects associated with Metoclopramide include: Restlessness; Drowsiness; Fatigue; Dizziness; Tardive dyskinesia.