Proton Pump Inhibitors (PPIs) — Nutrient Depletion & Health Patterns
Also known as: Omeprazole, Esomeprazole, Lansoprazole, Pantoprazole
Drug Class: Gastrointestinal
Medications that reduce stomach acid production by blocking proton pumps, significantly altering gut microbiome and immune function.
Nutrients That Proton Pump Inhibitors (PPIs) May Deplete
Long-term use of Proton Pump Inhibitors (PPIs) is associated with lower levels of the following nutrients based on peer-reviewed clinical research. WePattern surfaces these patterns from its clinical Knowledge Graph.
- Vitamin B12
- Iron
- Magnesium
- Calcium
- Vitamin D
- Folate
- Zinc
Common Side Effects of Proton Pump Inhibitors (PPIs)
- Gut dysbiosis
- Increased infection risk
- Nutrient malabsorption
- Bone fractures
- Kidney disease
Key Drug Interactions — Proton Pump Inhibitors (PPIs)
Proton Pump Inhibitors (PPIs) has 4 documented drug-drug interactions in WePattern's Pattern Health Intelligence database. Key interactions include:
- Clopidogrel
- Warfarin
- Antibiotics
- Iron supplements
Frequently Asked Questions
Does Proton Pump Inhibitors (PPIs) deplete nutrients?
Yes. Proton Pump Inhibitors (PPIs) has been associated with depletion of Vitamin B12, Iron, Magnesium, Calcium, Vitamin D, Folate, Zinc based on clinical research. WePattern maps these relationships from peer-reviewed sources.
What nutrients does Proton Pump Inhibitors (PPIs) deplete?
Proton Pump Inhibitors (PPIs) is associated with lower levels of: Vitamin B12, Iron, Magnesium, Calcium, Vitamin D, Folate, Zinc. These depletions can develop over weeks to months of regular use.
What are the side effects of Proton Pump Inhibitors (PPIs)?
Common side effects associated with Proton Pump Inhibitors (PPIs) include: Gut dysbiosis; Increased infection risk; Nutrient malabsorption; Bone fractures; Kidney disease.