Spironolactone — Nutrient Associations & Health Patterns
Also known as: Spironolactone (Aldactone, CaroSpir)
Drug Class: Potassium-sparing diuretic / Androgen blocker
Potassium-sparing diuretic and aldosterone antagonist used for heart failure, fluid retention, high blood pressure, and hormonal conditions including PCOS, hormonal acne, and female pattern hair loss. Blocks androgen receptors — popular off-label for skin and hair in women. Only evidence-qualified catalog relationships are listed here. Other catalog entries remain unverified in this reference; absence from the list does not rule out other medication effects or interactions.
Medication and Nutrition Context
Only evidence-qualified catalog relationships are listed here. Other catalog entries remain unverified in this reference; absence from the list does not rule out other medication effects or interactions.
Common Side Effects of Spironolactone
- Elevated potassium (hyperkalemia)
- Breast tenderness
- Irregular periods
- Dizziness
- Low sodium (hyponatremia)
- Increased urination
- Fatigue
- Breast growth in men (gynecomastia)
Key Drug Interactions — Spironolactone
Spironolactone has 9 documented drug-drug interactions in WePattern's Pattern Health Intelligence database. Key interactions include:
- Potassium supplements (DANGEROUS — can cause fatal hyperkalemia)
- ACE inhibitors
- ARBs
- NSAIDs
- Digoxin
- Lithium
Frequently Asked Questions
What nutrient associations are reported for Spironolactone?
Only evidence-qualified catalog relationships are listed here. Other catalog entries remain unverified in this reference; absence from the list does not rule out other medication effects or interactions.
Which nutrient relationships are mapped for Spironolactone?
Only evidence-qualified catalog relationships are listed here. Other catalog entries remain unverified in this reference; absence from the list does not rule out other medication effects or interactions.
What are the side effects of Spironolactone?
Common side effects associated with Spironolactone include: Elevated potassium (hyperkalemia); Breast tenderness; Irregular periods; Dizziness; Low sodium (hyponatremia).