Spironolactone — Nutrient Associations & Health Patterns
Also known as: Spironolactone (Aldactone, CaroSpir)
Drug Class: Potassium-sparing diuretic / Androgen blocker
Spironolactone is a Potassium-sparing diuretic / Androgen blocker that may affect nutrient status or medication timing in some contexts. WePattern Pattern Health Intelligence maps evidence-qualified nutrient associations, side effects, and interaction context linked to Spironolactone.
Reported Nutrient Associations for Spironolactone
Peer-reviewed research reports relationships involving the following nutrients. WePattern surfaces them as evidence-qualified associations; they do not establish deficiency, causation, or a fixed timeline for an individual.
- Zinc
- Folic acid
- Sodium
- Calcium
Common Side Effects of Spironolactone
- Elevated potassium (hyperkalemia)
- Breast tenderness
- Irregular periods
- Dizziness
- Low sodium (hyponatremia)
- Increased urination
- Fatigue
- Breast growth in men (gynecomastia)
Key Drug Interactions — Spironolactone
Spironolactone has 9 documented drug-drug interactions in WePattern's Pattern Health Intelligence database. Key interactions include:
- Potassium supplements (DANGEROUS — can cause fatal hyperkalemia)
- ACE inhibitors
- ARBs
- NSAIDs
- Digoxin
- Lithium
Frequently Asked Questions
What nutrient associations are reported for Spironolactone?
Spironolactone has reported nutrient associations involving Zinc, Folic acid, Sodium, Calcium in clinical research. This does not establish that every person will become deficient or that the medication caused an individual result.
Which nutrient relationships are mapped for Spironolactone?
WePattern maps reported associations involving: Zinc, Folic acid, Sodium, Calcium. The strength, mechanism, dose, duration, and clinical relevance vary, so a clinician or pharmacist should interpret them in context.
What are the side effects of Spironolactone?
Common side effects associated with Spironolactone include: Elevated potassium (hyperkalemia); Breast tenderness; Irregular periods; Dizziness; Low sodium (hyponatremia).