Trazodone — Nutrient Associations & Health Patterns
Also known as: Trazodone hydrochloride (Desyrel, Oleptro)
Drug Class: SARI Antidepressant / Sleep aid
Trazodone is a SARI Antidepressant / Sleep aid that may affect nutrient status or medication timing in some contexts. WePattern Pattern Health Intelligence maps evidence-qualified nutrient associations, side effects, and interaction context linked to Trazodone.
Reported Nutrient Associations for Trazodone
Peer-reviewed research reports relationships involving the following nutrients. WePattern surfaces them as evidence-qualified associations; they do not establish deficiency, causation, or a fixed timeline for an individual.
- CoQ10
- Vitamin B12
- Melatonin
- Magnesium
- Vitamin B6
Common Side Effects of Trazodone
- Drowsiness (used therapeutically for sleep)
- Dizziness
- Dry mouth
- Blurred vision
- Low blood pressure
- Headache
- Nausea
- Priapism (rare but serious in men)
Key Drug Interactions — Trazodone
Trazodone has 8 documented drug-drug interactions in WePattern's Pattern Health Intelligence database. Key interactions include:
- MAOIs (deadly — 14-day washout)
- Other serotonin-affecting drugs (serotonin syndrome)
- Blood pressure medications (additive lowering effect)
- Digoxin
- Warfarin
- CNS depressants and alcohol (additive sedation)
Frequently Asked Questions
What nutrient associations are reported for Trazodone?
Trazodone has reported nutrient associations involving CoQ10, Vitamin B12, Melatonin, Magnesium, Vitamin B6 in clinical research. This does not establish that every person will become deficient or that the medication caused an individual result.
Which nutrient relationships are mapped for Trazodone?
WePattern maps reported associations involving: CoQ10, Vitamin B12, Melatonin, Magnesium, Vitamin B6. The strength, mechanism, dose, duration, and clinical relevance vary, so a clinician or pharmacist should interpret them in context.
What are the side effects of Trazodone?
Common side effects associated with Trazodone include: Drowsiness (used therapeutically for sleep); Dizziness; Dry mouth; Blurred vision; Low blood pressure.